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Influence of tumour micro-environment heterogeneity on therapeutic response

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This protects skin cells from damage, which helps slow down the visible signs of aging

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The primary molecular actions relevant to skin are: modulation of TGF- signaling (upregulating TGF-1 for collagen I/III synthesis while suppressing TGF-2 to prevent scarring), decorin upregulation for orderly collagen fibril assembly, MMP suppression paired with TIMP upregulation to preserve ECM integrity, and copper-dependent lysyl oxidase activation for collagen crosslinking

Abstract To investigate the impact of Glutathione (GSH) in mitigating low-temperature stress in Pusa Sheetal cv